Capacity of a Double cone blender is described in term of Liters. To Determine capacity in kgs the density of a powder is measured n then multiplied by Liters. Capacity iñterm of liters remain fix but in kgs vary depending upon density of powder.
In this regard, how do you calculate batch size in KG?
Divide milligrams to 1000 to get value in the gram and then again Divide by 1000 to get values in kilograms(mg÷1000÷1000).
In respect to this, how is equipment capacity calculated in pharmaceutical industry?
Capacity Calculation of Coating Machine
- Coating pan capacity calculation formula.
- Maximum capacity of coating pan (Kg) = Brim volume of pan (ltrs) x Bulk density of tablets (g/ml)
- Minimum capacity of coating pan = Brim volume of pan (ltrs) x Bulk density of tablets (g/ml) x 60/100.
How is equipment occupancy calculated?
For example maximum occupancy for 200 litre equipment shall be calculated as 200 litre x 0.5 gm/ml = 100.00 Kg.
Occupancy rate is the percentage of occupied rooms in your property at a given time. It is one of the most high-level indicators of success and is calculated by dividing the total number of rooms occupied, by the total number of rooms available, times 100, creating a percentage such as 75% occupancy.
Claimed capacity is provided by vendor in liters and to calculate capacity in kgs,first calculate bulk density of powder to be mixed and then it is multiplied by capacity in liters. claimed capaciy in liters is 400 liter and bulk density is 0.8 then capacity in kgs is 400*0.8=320kg.
A V blender is a type of equipment that the pharmaceutical industry uses for various blending applications. The primary reason V blender mixing is so critical for the pharmaceutical industry is because pharma companies must adhere to strict production guidelines.
As a rule of thumb, working capacity of a blender is usually determined as 50% of the total volume of the blender. For example, if a blender has an actual volume of 2 ft3, then the working capacity will be 1 ft3. While blenders are generally sized according to volume, powders are usually measured according to density.
The chopper does not have any advantage on the size of granules when the impeller speed is high( about 200 rpm). The process of convert wet mass into granules is called Kneading.
End Point in a wet granulation process is characterized by rheological properties of the wet mass such as density, viscosity etc which are in turn a function of particle size, shape and other physical properties.
Endpoint can be defined as a target particle size mean or distribution. a) Power Consumption. Power consumption of the mixer motor for end-point determination and scale-up is widely used because the measurement is economical, does not require extensive mixer modifications and is well correlated with granule growth.
The V-mixer machine is a type of mixing machine that achieves homogeneous mixing of materials through the movement of the mixing vessel. The movement takes place clearly in the two arms of the cylinder, which are inclined at an angle of 70° to 90°, forming a “V” shaped design.
V mixers are rotary mixers, also called tumble blenders. The whole shell, which has a shape of a V and is made of 2 cylinders welded at 75° to 90°, is rotated allowing to mix the components thanks to a diffusive mixing.